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Vials and ampoules

Vials and ampoules are widely used in the pharmaceutical industry for liquids, injectables and vaccines. These small glass containers require extremely accurate and durable labelling, as the information – batch number, best-before date, serial number and 2D/Datamatrix codes – must remain clear throughout the product’s lifecycle, even after sterilization, cold storage and transportation.
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Automatic vial labelling labelling solution for vials

Different techniques for Vials and ampoules

UV Laser - Marking on glass bottles
Product marking laser marking yellow dark glass

Laser marking

Laser marking is the most precise and permanent method for glass ampoules and vials. The marking is non-contact and creates a frosted or contrasting code on the glass surface, making it both legible and sterile. Since no paint or ink is used, the process is free from contamination risk.

Advantages:

  • Permanent marking that can withstand sterilization, autoclaving and refrigerated storage.
  • No contact with the product – sterile and GMP compliant.
  • Perfect for 2D/Datamatrix codes on small surfaces.
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Bläckmärkning vialer och ampuller ex. batchnummer
Bläckmärkning vialer och ampuller med ex batchnummer

Inkjet printing

Ink marking is a fast and flexible option, especially suitable for high-speed lines. With the right type of ink – such as UV-resistant or heat-resistant ink – the marking can withstand both sterilization and transport. The technology is often used for batch numbers, best-before dates and simple identification codes.

Advantages:

  • Very fast labelling in continuous production lines.
  • Works on both glass and plastic vials.
  • Cost-effective and easy to integrate into existing equipment.
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Automatisk etiketteringslösning för vialer ampuller etikett
Labelling machine - Automatic vial labelling labelling solution for vials
Labelling machine - Automatic vial labelling labelling solution for vials

Labelling

Labelling is used when the vial or ampoule needs additional information, security seals or designed labels. Wrap-around labels allow the entire circumference of the container to be used to display text, codes and logos. The labels can also contain variable data that is printed in real time using thermal transfer (TTO) or ink.

Advantages:

  • Provides space for more information than direct labelling.
  • Possibility of security labels and sealing solutions.
  • Can be combined with variable printing and vision control.
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Read more about Vials and ampoules

Vials and ampoules are widely used in the pharmaceutical industry for liquids, injectables and vaccines. These small glass containers require extremely accurate and durable labelling, as the information – batch number, best-before date, serial number and 2D/Datamatrix codes – must remain clear throughout the product’s lifecycle, even after sterilization, cold storage and transportation.

A particular challenge when labelling vials is balance and stability during production. Since the liquid is often in the upper part of the vial while the bottom is empty glass, the center of gravity is high. This makes the vial more prone to falling or wobbling during rapid handling, especially when traveling on a conveyor belt. Therefore, equipment with precise product control, smooth handling and vibration-free labelling is required to ensure both accuracy and safety.

In addition, the surface is often round, small and sometimes transparent, which places high demands on contrast, focus and stability of the marking technology. The marking must be done contact-free and with great precision to avoid contamination or damage to the packaging.

Challenges when labelling vials and ampoules:

  • Small and rounded surfaces make placement and focus critical.
  • Transparent materials require high contrast or special inks.
  • Sterilization and refrigerated storage can affect the adhesion of the ink.
  • High speeds in the production line require fast, precise systems.

For pharmaceutical products in glass vials and ampoules, we recommend laser marking for permanent and sterile marking that meets GMP and FMD requirements. For high-speed production of variable data, inkjet marking (CIJ) is an effective choice. If the packaging requires more space for information, or when security sealing is necessary, labelling with wrap-around or TTO printing is the optimal solution.

Combined with vision systems for code quality control and positioning, our solutions ensure that every label is accurate, verified and fully traceable – for safe and reliable pharmaceutical production.

Questions & Answers (FAQ)

Yes. Laser marking allows you to mark directly on the glass surface without affecting the product contents. The laser creates a frosted, permanent marking that is both sterile and durable – ideal for medical products that require high hygiene standards.
Laser is the most durable method for autoclaving, as the marking is burned into the glass surface and is not affected by heat, steam or chemicals. For easier marking, heat and moisture resistant inks can also be used.
Yes. Our inkjet and laser markers are designed to handle curved surfaces with high precision. The marking head follows the shape of the product and can be placed on hard-to-reach surfaces without contact.
Absolutely. Wrap-around labels are often used to combine information, traceability and branding. They can be applied automatically and supplemented with variable data such as batch numbers and barcodes.
Our integrated vision systems check the labelling in real time. The camera verifies that text and codes are complete, readable and correctly positioned – an important part of quality control in GMP production.
For high production speeds, inkjet marking is often the most cost-effective. For premium products or long-term durability, laser is a better investment due to minimal maintenance and no consumables.
Yes. We offer solutions where labelling, laser and vision inspection can be combined to create a comprehensive system with traceability, product identification and safety features according to FMD and GMP standards.

Book a demo

Do you want to see how the machine works in your production on your material or product? Book a free Demo We will be happy to show you the machine (or similar machine) in operation and how we can tailor the solution based on your needs.

Fill out the form and we will contact you!  

You can also call us directly at + 4610-444 1600.